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MagnetOs Clinical Evidence

Use of novel biphasic calcium phosphate with submicron surface topography in posterolateral fusion

The purpose of this evaluation of a consecutive case series was to assess radiographic success, functional and pain outcomes following posterolateral lumbar fusion using a novel biphasic calcium phosphate bone graft with a unique submicron topography (MagnetOs™, Kuros Biosciences, B.V.).

Four female patients with an average age at the time of surgery of 62.7 (50-70 years of age) underwent a single or a two-level posterolateral fusion procedure for the treatment of degenerative spondylolisthesis or deformity using MagnetOs over the transverse processes and/or the facet joints. Each of these cases involved a perimenopausal/postmenopausal woman; a life stage known to negatively affect bone quality and cause concern when aiming for a successful fusion outcome.

Anteroposterior and lateral radiographs, visual analog scale (VAS) for back and leg pain, Oswestry Disability Index (ODI), and medication usage were reviewed pre-operatively and post-operatively at 2, 3, 6, and 12 months. VAS and ODI scales were not available at 12 months; however, considering the marked improvement reported by each patient at 6 months, little significant improvement at this time point would be appreciated.