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Kuros Biosciences announces publication of data on MagnetOs in eCM Journal linking MOA to enhanced predictable bone regeneration
Schlieren (Zurich), Switzerland, 22, 2021 – Kuros Biosciences (SIX: KURN) today announced the publication of new data in eCM Journal, a peer-reviewed publication focusing on preclinical re-search in the musculoskeletal field, on the mechanism of action of its MagnetOs bone graft.
The paper describes how immunomodulation by bone grafts with submicron topographical fea-tures translates to enhanced bone regeneration and successful spinal fusion. This is the first and only fully-translational peer-reviewed article for a bone graft material, describing evidence of its performance from benchtop to the clinic.
Joost de Bruijn, Chief Executive Officer of Kuros, said: “This first peer-reviewed publication in-cluding real-life clinical data with MagnetOs outlines how our product can make a significant difference to patients by delivering uniform, stable and reliable bone fusions.”
“Previous bone grafts have been supported by pre-clinical data which have not translated to the equivalent clinical experience, driving skepticism amongst spine surgeons about the efficacy of synthetic products. This article in eCM Journal clearly outlines the excellent efficacy of Magne-tOs in both preclinical and clinical studies. It particularly highlights MagnetOs’ submicron sur-face structure, which is designed to direct early wound healing toward a bone-forming pathway to support predictable healing and reliable fusion.”
Kuros helps patients live fuller, more active lives by giving surgeons the technology they need to eliminate non-unions. MagnetOs bone graft achieves this with a unique surface design proven to unlock the untapped power of the body’s immune system by growing new bone throughout the graft – for more predictable fusions. The eCM Journal article highlighted the following key points:
For the full article in eCM Journal, click here.
For further information, please contact:
|Kuros Biosciences AG
|Chief Financial Officer
|Tel +41 44 733 47 47
|+44 7483 284 853
MagnetOs bone graft has an advanced submicron surface topography that leads to the formation of bone in spinal fusion defects rather than scar tissue. In preclinical models, MagnetOs preferentially directs the body’s early wound healing response toward the bone-forming pathway, an effect that is so potent that bone can be formed even in soft tissues without the need for added cells or growth factors. This ground-breaking research led to Kuros attaining an osteoinductive claim for MagnetOs in Europe and it is now supported by more than three years of clinical experience since its launch in the United Kingdom in May 2017. Results from in vitro or in vivo laboratory testing may not be predictive of clinical experience in humans. MagnetOs is not cleared by TGA or FDA as an osteoinductive bone graft.
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About Kuros Biosciences AG
Kuros Biosciences is a leader in next generation synthetic bone graft technologies for targeted and controlled bone healing. Kuros’s bone graft substitute, MagnetOs, is commercialized in the U.S. and UK for use in posterolateral spinal fusions. Kuros’s lead product in development, Fibrin PTH, a drug-biologic combination for spinal interbody fusion, has entered into a phase 2 clinical trial in the U.S. Kuros is located in Schlieren (Zurich), Switzerland, Bilthoven (The Netherlands) and Burlington (MA), U.S. The Company is listed according to the International Reporting Standard on the SIX Swiss Exchange under the symbol KURN. Visit www.kurosbio.com for additional information on Kuros, its science and product pipeline.
Forward Looking Statements
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