MagnetOs Granules

MagnetOs™ Granules is our original advanced bone graft based on the submicron needle-shaped NeedleGrip™ surface technology.  It forms the foundation of all MagnetOs formulations and is the driver of our mechanism of action. 

Evidence isn’t optional for Kuros. We are committed to generating high-quality evidence, enabling our team to discover, develop and deliver innovative biologic technologies with one goal in mind: To give surgeons the confidence to make evidence-based decisions for their patients.

These efforts to mimic the best features of biologically robust autograft bone led to the creation of MagnetOs as it is today.

Proven foundation 

MagnetOs Granules is the basis for all MagnetOs formulations and has been CE-marked since 2017. This foundational technology is supported by an unprecedented blend of scientific, preclinical, and clinical studies through our global research program, Project Fusion.¹  

Powered by harnessing the immune system 

MagnetOs is capable of polarizing macrophages from the M1 pro-inflammatory to the M2 pro-healing phenotype, which is known to influence bone growth through secretion of proteins such as BMP-2. Pre-clinical studies have demonstrated the osteoinductive potential of MagnetOs without added cells or growth factors.^†‡2-6 These features combine to make MagnetOs a proven and trusted choice for providing predictable fusions.¹

Equivalent to autograft 

In fact, MagnetOs Granules as a standalone bone graft reached higher fusion rates than the gold standard of autograft. This is based on results of an observer blinded, randomized, controlled, intrapatient, multi-center clinical trial of instrumented posterolateral fusions, as assessed by fine-cut CT scans at one year follow-up published in Spine.¹ 

The MagnetOs Granules technology is also proven to be equivalent to autograft for spinal fusions in multiple pre-clinical models.^*†¶1-6