MagnetOs Granules

MagnetOs™ Granules is the original form of our advanced bone graft based on the submicron needle-shaped NeedleGrip™ surface technology. It remains the foundation of all MagnetOs formulations and is the driver of our mechanism of action for bone generation in the extremities.​
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Evidence isn’t optional for Kuros. We are committed to generating high-quality evidence, enabling our team to discover, develop and deliver innovative biologic technologies with one goal in mind: To give surgeons the confidence to make evidence-based decisions for their patients.

These novel innovations have revealed a powered mechanism of action for bone growth, offering tremendous promise for predictable fusions and traumatic reconstructions of the extremity.​

Predictable handling​

Packaged in granule form without any carrier, MagnetOs Granules lends itself to growing bone in amorphous and contained or semi-contained voids.​^1-3
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Proven foundation

MagnetOs Granules are the basis for all MagnetOs formulations and have been 510(k)-cleared since 2017. This foundational technology is supported by an unprecedented blend of scientific, preclinical, and clinical studies through our global research program, Project Fusion.^1,3

Powered by harnessing the immune system ​

Macrophages polarize to the M2 phenotype, which are pro-healing and upregulate stem cells to create bone.^1,2 MagnetOs NeedleGrip surface technology enhances the pathway to M2 macrophages.^*†2,3 Furthermore, MagnetOs has demonstrated the ability to form bone in a canine intramuscular pouch model without the addition of cells or growth factors.^*†‡4 These understandings and evidence combine to define MagnetOs as a powered solution for predictable fusions and traumatic reconstructions of the extremity.​

Equivalent to autograft ​

In fact, MagnetOs Granules as a standalone bone graft reached higher fusion rates than the gold standard of autograft. This is based on results of an observer blinded, randomized, controlled, intrapatient, multi-center clinical trial of instrumented posterolateral fusions of the spine, as assessed by fine-cut CT scans at one year follow-up.^{5 ​}
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The MagnetOs Granules technology is also proven to be equivalent to autograft for spinal fusions in multiple pre-clinical models.^*§6,7