International

Where are you?

To give you the most accurate information about our products and what we can do for you, we need to direct you to the right site.

USA International

Grow bone with
the new MagnetOsTM MIS

Engineered for precise delivery and predictable fusions

Learn more
Close

MagnetOs Granules

MagnetOs Granules bone graft for fusion

Move the needle in fusion with our foundational, proven solution

MagnetOs™ Granules is our original advanced bone graft based on the submicron needle-shaped NeedleGrip™ surface technology.  It forms the foundation of all MagnetOs formulations and is the driver of our mechanism of action. 

Evidence isn’t optional for Kuros. We are committed to generating high-quality evidence, enabling our team to discover, develop and deliver innovative biologic technologies with one goal in mind: To give surgeons the confidence to make evidence-based decisions for their patients.

These efforts to mimic the best features of biologically robust autograft bone led to the creation of MagnetOs as it is today. 

Proven foundation

MagnetOs Granules is the basis for all MagnetOs formulations and has been 510(k)-cleared since 2017. This foundational technology is supported by an unprecedented blend of scientific, preclinical, and clinical studies through our global research program, Project Fusion.

Powered by harnessing the immune system 

Macrophages polarize to the M2 phenotype, this phenotype is pro-healing and upregulates stem cells to create bone.1,2 MagnetOs NeedleGrip surface technology enhances the pathway to M2 macrophages.*†2,3

MagnetOs has been shown in pre-clinical studies to form bone even in soft tissue without added cells or growth factors.*†‡4 These features combine to make MagnetOs a proven and trusted choice for providing predictable fusions.5

Equivalent to autograft 

In fact, MagnetOs Granules as a standalone bone graft achieved higher fusion rates than the gold standard of autograft. This is based on results of an observer blinded, randomized, controlled, intrapatient, multi-center clinical trial of instrumented posterolateral fusions, as assessed by fine-cut CT scans at one year follow-up.5 

The MagnetOs Granules technology is also proven to be equivalent to autograft for spinal fusions in multiple pre-clinical models.*§6,7

Evidence

Explore the MagnetOs vast body of evidence with “Project Fusion”

MOA

Learn how the MagnetOs mechanism of action ​grows bone

Product code     Volume (CC)     Granule size (mm)

703-021-US         10                       1 – 2

703-045-US         20                       1 – 2

703-026-US         20                       2 – 4

Download brochure

Want to learn more about MagnetOs Granules?

Book your own appointment with one of our scientific experts.

Set Up Meeting

References and Disclaimers

Expand
Nothing to display.

*Results from in vitro or in vivo laboratory testing may not be predictive of clinical experience in humans. For important safety and intended use information please visit kurosbio.com.

† MagnetOs is not cleared by the FDA or TGA as an osteoinductive bone graft.

‡ In large animal models

§MagnetOs has been proven to generate more predictable fusions that two commercially available alternatives in an ovine model of posterolateral fusion

  1. Italiani, et al. Front Immunol. 2014;5:514.
  2. Loi, et al. Stem Cell Res Ther. 2016;7:15.
  3. Van Dijk, et al. 2021;41:756-73.
  4. Duan, et al. 2019;37:60-73.
  5. Stempels, et al. Spine. 2024;49(19):1323-1331.
  6. Van Dijk, et al. JOR Spine. 2018;e1039.
  7. Van Dijk, et al. J Biomed Mater Res. Part B: Appl Biomater. 2019;107(6):2080-2090.

MAT-0221