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Translation

We are the first and only company to translate evidence from benchtop through to patient in a reliable way. To discover how, watch these five short videos (or read the articles below).

Van Dijk, et al. Clin Spine Surg. 2020;33(6):E276-E287.

Van Dijk, et al. Clin Spine Surg. 2020;33(6):E276-E287.

Van Dijk, et al. JOR Spine. 2018;e1039.

Van Dijk, et al. JOR Spine. 2018;e1039.

Van Dijk, et al. J Biomed Mater Res. Part B: Appl Biomater. 2019;107(6):2080-2090.

Van Dijk, et al. J Biomed Mater Res. Part B: Appl Biomater. 2019;107(6):2080-2090.

Duan, et al. eCM. 2019;37:60-73.

Duan, et al. eCM. 2019;37:60-73.

Van Dijk, et al. Manuscript in submission.

Van Dijk, et al. Manuscript in submission.

Journal Articles

Scientific Evidence

Calcium phosphate with submicron topography upregulates M2 phenotype in primary human macrophages, enhancing downstream angiogenesis and osteogenesis in vitro.

L.A. van Dijk, L. Utomo, H. Yuan, F. de Groot, D. Gawlitta, A.J.W.P. Rosenberg, and J.D. de Bruijn.

Manuscript in submission

Preclinical Evidence

MagnetOs, Vitoss, and Novabone in a Multi-endpoint Study of Posterolateral Fusion: A True Fusion or Not? 

L.A. van Dijk, F. de Groot, A.J.W.P Rosenberg, M. Pelletier, C. Christou, and J.D. de Bruijn, W.R. Walsh.Clin Spine Surg.2020;33(6):E276-E287.

Full article available here

Biphasic calcium phosphate with submicron surface topography in an Ovine model of instrumented posterolateral spinal fusion.

L.A. van Dijk, R. Duan, X. Luo, D. Barbieri , M. Pelletier, C. Christou, A.J.W.P. Rosenberg, H. Yuan, F. de Groot, W.R. Walsh, and J.D. de Bruijn.JOR Spine.2018;e1039.

Full article available here

Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion.

L.A. van Dijk, D. Barbieri, F. de Groot, Huipin Yuan, R. Oliver, C. Christou, W.R. Walsh, and J.D. de Bruijn.J Biomed Mater Res B Appl Biomater.2019;107(6):2080-2090.

Full article available here

Accelerated bone formation by biphasic calcium phosphate with a novel sub-micron surface topography. 

R. Duan, L.A. van Dijk, D. Barbieri, F. de Groot, H. Yuan, and J.D. de Bruijn.eCM.2019;37:60-73.

Full article available here

Learn more how we are generating a clinical data package that is far superior to any other bone graft cleared for use via the same regulatory pathway.